Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27381155 | 0.92 | CTSC (0.73) | CTSCKCNH2 | |
| SCHEMBL30738859 | 0.92 | CTSC (0.73) | CTSCKCNH2 | |
| SCHEMBL32680926 | 0.92 | CTSC (0.73) | CTSCKCNH2 | |
| SCHEMBL27380953 | 0.91 | CTSC (0.73) | CTSCKCNH2 | |
| Trifluoroacetic Acid SCHEMBL16478370 | 0.89 | CTSC (0.69) | CTSCKCNH2 | |
| SCHEMBL27380954 | 0.89 | CTSC (0.74) | CTSCKCNH2 | |
| SCHEMBL30738910 | 0.89 | CTSC (0.74) | CTSCKCNH2 | |
| Trifluoroacetic Acid SCHEMBL16478344 | 0.88 | CTSC (0.68) | CTSCKCNH2 | |
| SCHEMBL27381046 | 0.88 | CTSC (0.76) | CTSCKCNH2 | |
| SCHEMBL288984 | 0.88 | CTSC (0.72) | CTSCKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427445-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | AstraZeneca AB (SE) | 2012-03-14 | — | — | EP | claimed |
| EP-2427445-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | AstraZeneca AB (SE) | 2012-03-14 | — | — | EP | disclosed |