Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28976582 | 0.89 | PARP1 (0.41) | PARP1PARP2OPRL1BTKCYP2D6 | |
| SCHEMBL28976477 | 0.81 | PARP1 (0.47) | PARP1PARP2OPRL1CYP2D6CYP2B6 | |
| SCHEMBL28976340 | 0.80 | PARP1 (0.38) | PARP1PARP2OPRL1BTKSCN5A | |
| SCHEMBL30755499 | 0.75 | PARP1 (0.46) | PARP1PARP2OPRL1 | |
| SCHEMBL30526942 | 0.75 | PARP1 (0.46) | PARP1PARP2OPRL1 | |
| SCHEMBL14837702 | 0.75 | PARP1 (0.36) | PARP1PARP2CYP2D6CYP2B6OPRM1 | |
| SCHEMBL22208503 | 0.74 | NOTUM (0.53) | OPRL1NOTUM | |
| SCHEMBL28976710 | 0.73 | KDM1A (0.41) | PARP1OPRM1SCN5ASCN9AKDM1A | |
| SCHEMBL28976476 | 0.72 | SCN10A (0.41) | PARP1PARP2SCN5ASCN9AKDM1A | |
| SCHEMBL14837700 | 0.72 | PARP1 (0.36) | PARP1PARP2BTKCYP2D6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115884810-A | Imidazopyridazines as IL-17 modulators | 詹森药业有限公司 | 2023-03-31 | — | — | CN | disclosed |