Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 4/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.47 |
| ▸ | RRM1 | P23921 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28142472 | 1.00 | PAOX (0.53) | PAOXALDH1A1TSHRS1PR2S1PR4 | |
| Acetic Acid SCHEMBL29134629 | 1.00 | PAOX (0.53) | PAOXALDH1A1TSHRS1PR2S1PR4 | |
| Acetic Acid SCHEMBL28238933 | 0.98 | PAOX (0.55) | PAOXALDH1A1TSHRS1PR2S1PR4 | |
| Acetic Acid SCHEMBL11789828 | 0.98 | PAOX (0.55) | PAOXALDH1A1TSHRS1PR2S1PR4 | |
| Acetic Acid SCHEMBL28328612 | 0.98 | PAOX (0.55) | PAOXALDH1A1TSHRS1PR2S1PR4 | |
| Acetic Acid SCHEMBL4073583 | 0.98 | PAOX (0.55) | PAOXALDH1A1TSHRS1PR2S1PR4 | |
| Acetic Acid SCHEMBL27657767 | 0.98 | PAOX (0.55) | PAOXALDH1A1TSHRS1PR2S1PR4 | |
| Acetic Acid SCHEMBL28361106 | 0.98 | PAOX (0.55) | PAOXALDH1A1TSHRS1PR2S1PR4 | |
| Acetic Acid SCHEMBL27677746 | 0.98 | PAOX (0.55) | PAOXALDH1A1TSHRS1PR2S1PR4 | |
| Acetic Acid SCHEMBL27983825 | 0.98 | PAOX (0.55) | PAOXALDH1A1TSHRS1PR2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110194462-B | Two-dimensional nanoscale ultrathin talcum sheet and preparation method thereof | 中国科学院上海硅酸盐研究所 | 2023-03-28 | — | — | CN | claimed |
| CN-117342912-A | Method for producing BTX from aromatic-rich light pyrolysis distillate | 中国石油化工股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-115999628-A | Hydrocracking catalyst, preparation method and application thereof, and aromatic-rich cracking distillate hydrocracking method | 中国石油化工股份有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-110194462-B | Two-dimensional nanoscale ultrathin talcum sheet and preparation method thereof | 中国科学院上海硅酸盐研究所 | 2023-03-28 | — | — | CN | disclosed |