Bromide

Bromide

SCHEMBL28977646

Br.C=CCN1C=CN(CCC)C1C

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA2B P29275 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20375332 0.87 TSHR (0.32)
SCHEMBL7192288 0.85 PRCP (0.32)
SCHEMBL9940095 0.84 TSHR (0.36)
Hydrochloric Acid SCHEMBL16391002 0.83 PRCP (0.31)
Bromide SCHEMBL28422476 0.80
Hydrochloric Acid SCHEMBL29109677 0.76
Bromide SCHEMBL29268458 0.76
SCHEMBL487097 0.74
Bromide SCHEMBL28092799 0.73
SCHEMBL5287172 0.73 GBA1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115867586-A Electrochemically debondable adhesive compositions 汉高股份有限及两合公司 2023-03-28 CN disclosed