Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28978056 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP2C19CHRM4NPC1RAB9A | |
| SCHEMBL29201718 | 0.86 | CHRM4 (0.50) | SMN1; SMN2CYP2C19CHRM4NPC1RAB9A | |
| SCHEMBL31677181 | 0.85 | CHRM4 (0.52) | SMN1; SMN2CYP2C19CHRM4NPC1RAB9A | |
| SCHEMBL29384528 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP2C19CHRM4NPC1RAB9A | |
| SCHEMBL28978001 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP2C19CHRM4NPC1RAB9A | |
| SCHEMBL618472 | 0.80 | SMN1; SMN2 (0.74) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL8765520 | 0.80 | SMN1; SMN2 (0.62) | SMN1; SMN2CYP2C19CHRM4NPC1RAB9A | |
| SCHEMBL15140566 | 0.79 | SMN1; SMN2 (0.72) | SMN1; SMN2CYP2C19CHRM4NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL716107 | 0.79 | SMN1; SMN2 (0.72) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL15009674 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2CYP2C19CHRM4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710274-A | IRAK4 degradation agent, preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2023-02-24 | — | — | CN | disclosed |