Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.66 |
| ▸ | JAK3 | P52333 | 20/20 | 0.66 |
| ▸ | JAK1 | P23458 | 16/20 | 0.66 |
| ▸ | JAK2 | O60674 | 16/20 | 0.66 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.58 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28979015 | 0.95 | TYK2 (0.64) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL24174463 | 0.92 | TYK2 (0.68) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL24175232 | 0.87 | TYK2 (0.66) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL24174785 | 0.87 | TYK2 (0.66) | TYK2JAK3JAK1JAK2P2RX3 | |
| Trifluoroacetic Acid SCHEMBL28978695 | 0.85 | JAK3 (0.60) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL18260446 | 0.81 | TYK2 (0.82) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL18260449 | 0.81 | TYK2 (0.82) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL24174487 | 0.80 | TYK2 (0.64) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL28978696 | 0.80 | TYK2 (0.64) | TYK2JAK3JAK1JAK2P2RX3 | |
| Trifluoroacetic Acid SCHEMBL28978706 | 0.80 | JAK3 (0.54) | TYK2JAK3JAK1JAK2P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916747-A | Fused heterocyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-04-04 | — | — | CN | disclosed |