Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.51 |
| ▸ | JAK3 | P52333 | 20/20 | 0.51 |
| ▸ | JAK2 | O60674 | 16/20 | 0.51 |
| ▸ | JAK1 | P23458 | 16/20 | 0.51 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.49 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28978686 | 0.93 | TYK2 (0.51) | TYK2JAK3JAK2JAK1P2RX3 | |
| SCHEMBL22055094 | 0.84 | TYK2 (0.53) | TYK2JAK3JAK2JAK1P2RX3 | |
| SCHEMBL24170331 | 0.81 | JAK3 (0.56) | TYK2JAK3JAK2JAK1P2RX3 | |
| SCHEMBL24175542 | 0.81 | JAK3 (0.56) | TYK2JAK3JAK2JAK1P2RX3 | |
| SCHEMBL30340362 | 0.81 | JAK3 (0.56) | TYK2JAK3JAK2JAK1P2RX3 | |
| SCHEMBL21574332 | 0.78 | TYK2 (0.71) | TYK2JAK3JAK2JAK1P2RX3 | |
| SCHEMBL30340340 | 0.77 | JAK3 (0.56) | TYK2JAK3JAK2JAK1P2RX3 | |
| SCHEMBL24175354 | 0.77 | JAK3 (0.56) | TYK2JAK3JAK2JAK1P2RX3 | |
| SCHEMBL22054123 | 0.77 | TYK2 (0.71) | TYK2JAK3JAK2JAK1P2RX3 | |
| SCHEMBL30227660 | 0.77 | TYK2 (0.71) | TYK2JAK3JAK2JAK1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916747-A | Fused heterocyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-04-04 | — | — | CN | disclosed |