Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTRA1 | Q92743 | 18/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21536106 | 1.00 | HTRA1 (0.58) | HTRA1CTSLCTSSCTSKACE | |
| SCHEMBL30335180 | 0.90 | HTRA1 (0.59) | HTRA1CTSLCTSSCTSK | |
| SCHEMBL19745348 | 0.90 | HTRA1 (0.59) | HTRA1CTSLCTSSCTSK | |
| SCHEMBL2687419 | 0.90 | HTRA1 (0.59) | HTRA1CTSLCTSSCTSK | |
| SCHEMBL19745347 | 0.90 | HTRA1 (0.59) | HTRA1CTSLCTSSCTSK | |
| SCHEMBL21506057 | 0.87 | HTRA1 (0.62) | HTRA1CTSLCTSSCTSK | |
| SCHEMBL29750937 | 0.87 | HTRA1 (0.62) | HTRA1CTSLCTSSCTSK | |
| SCHEMBL17859920 | 0.86 | HTRA1 (0.75) | HTRA1 | |
| SCHEMBL29399011 | 0.86 | HTRA1 (0.75) | HTRA1 | |
| SCHEMBL19744816 | 0.85 | HTRA1 (0.67) | HTRA1CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563033-B | Aliphatic prolinamide derivatives | 奥瑞恩眼科有限责任公司 | 2023-04-04 | — | — | CN | disclosed |