SCHEMBL28980053

SCHEMBL28980053

CC[C@H](OP(=O)(O)O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.46
LMNA P02545 2/20 0.44
SRC P12931 2/20 0.44
ACP3 P15309 3/20 0.42
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
AOC3 Q16853 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL759322 1.00 POLB (0.46) POLBLMNASRCACP3HPGD
SCHEMBL759321 0.85 POLB (0.44) POLBLMNASRCACP3HPGD
SCHEMBL9961560 0.83 POLB (0.43) POLBLMNAHPGDALOX15TSHR
SCHEMBL8435976 0.83 SMPD1 (0.45) POLBSRC
SCHEMBL28036264 0.82 KDM4E (0.39) POLBLMNAHPGDALOX15
SCHEMBL4943611 0.82 SMPD1 (0.51) POLB
SCHEMBL28233444 0.82 POLB (0.54) POLBSRCACP3NPSR1
SCHEMBL29025201 0.81 SRC (0.44) SRCACP3
SCHEMBL28370463 0.81 SRC (0.44) POLBSRCACP3
SCHEMBL8149764 0.81 CHRM2 (0.41) POLBSRCACP3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115724887-A Process for the synthesis of chiral alpha-phosphorus compounds 武汉大学 2023-03-03 CN disclosed