SCHEMBL28980967

SCHEMBL28980967

Nc1ccc(Cl)c(Oc2ncc(C(F)(F)F)cc2Cl)c1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.67
CYP3A4 P08684 1/20 0.67
CYP2C19 P33261 1/20 0.67
HPGD P15428 3/20 0.57
RAB9A P51151 1/20 0.52
KMT2A Q03164 1/20 0.51
SMN1; SMN2 Q16637 4/20 0.50
LMNA P02545 6/20 0.48
ALDH1A1 P00352 3/20 0.47
POLB P06746 2/20 0.47
HTT P42858 2/20 0.47
KDM4E B2RXH2 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
MAPT P10636 1/20 0.47
FFAR1 O14842 1/20 0.46
LIPE Q05469 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30366462 1.00 CYP1A2 (0.67) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL1154470 0.86 CYP1A2 (0.64) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL6098647 0.86 CYP1A2 (0.64) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL11269306 0.86 CYP1A2 (0.63) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL11268476 0.83 CYP1A2 (0.60) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL2711491 0.83 SMN1; SMN2 (0.65) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL11266695 0.82 CYP1A2 (0.69) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL31259495 0.81 CYP1A2 (0.54) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL2963408 0.81 CYP1A2 (1.00) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL6098527 0.80 CYP1A2 (0.60) CYP1A2CYP3A4CYP2C19HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024241082-A1 A SUBSTANTIALLY PURE FLUAZURON AND PREPARATION THEREOF HIKAL LIMITED (IN) 2024-11-28 WO claimed
CN-116768824-B Imide azole heterocyclic compound and application thereof 华南农业大学 2025-06-10 CN disclosed
WO-2024241082-A1 A SUBSTANTIALLY PURE FLUAZURON AND PREPARATION THEREOF HIKAL LIMITED (IN) 2024-11-28 WO disclosed
CN-116768824-A Imide azole heterocyclic compound and application thereof 华南农业大学 2023-09-19 CN disclosed
CN-115894351-A Preparation method of acetamiprid intermediate etherate 江苏天和制药有限公司 2023-04-04 CN disclosed
CN-111039858-B Preparation method of fluazuron 天和药业股份有限公司 2022-03-01 CN disclosed