Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308763 | 0.81 | — | — | |
| SCHEMBL308452 | 0.81 | — | — | |
| SCHEMBL19096064 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL377442 | 0.80 | HPGD (0.30) | — | |
| SCHEMBL4728514 | 0.75 | USP2 (0.38) | MAPK1 | |
| SCHEMBL27858888 | 0.70 | USP2 (0.33) | MAPK1 | |
| SCHEMBL27824848 | 0.70 | USP2 (0.33) | MAPK1 | |
| SCHEMBL324691 | 0.69 | USP2 (0.38) | MAPK1 | |
| Ammonia Solution, Strong SCHEMBL22169166 | 0.69 | USP2 (0.33) | MAPK1 | |
| SCHEMBL15825737 | 0.68 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916194-A | Methods for delaying, preventing and treating acquired resistance to RAS inhibitors | 锐新医药公司 | 2023-04-04 | — | — | CN | disclosed |