Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 7/20 | 0.42 |
| ▸ | JAK2 | O60674 | 12/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30295476 | 1.00 | ALK (0.42) | ALKJAK2MET | |
| SCHEMBL28982144 | 1.00 | ALK (0.42) | ALKJAK2MET | |
| SCHEMBL24006900 | 0.89 | ALK (0.33) | ALKJAK2 | |
| SCHEMBL28982136 | 0.88 | ALK (0.32) | ALK | |
| SCHEMBL30295481 | 0.88 | ALK (0.32) | ALK | |
| SCHEMBL28982137 | 0.88 | ALK (0.32) | ALK | |
| SCHEMBL30295428 | 0.87 | ALK (0.42) | ALKJAK2MET | |
| SCHEMBL28998897 | 0.83 | ALK (0.43) | ALKJAK2MET | |
| SCHEMBL30227983 | 0.83 | ALK (0.43) | ALKJAK2MET | |
| SCHEMBL30242757 | 0.81 | ALK (0.47) | ALKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916754-A | Heteroaromatic macrocyclic ether chemotherapeutic agents | 纽威伦特公司 | 2023-04-04 | — | — | CN | disclosed |