Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Dichloroethane SCHEMBL28182599 | 0.83 | TDP1 (0.61) | TDP1MEN1KMT2AALDH1A1 | |
| Methylene Chloride SCHEMBL30839315 | 0.79 | TDP1 (0.67) | TDP1MEN1KMT2AALDH1A1 | |
| Propylamine SCHEMBL1685445 | 0.78 | TDP1 (0.53) | TDP1MEN1KMT2AALDH1A1 | |
| Methylene Chloride SCHEMBL28228731 | 0.76 | TDP1 (0.61) | TDP1MEN1KMT2AALDH1A1 | |
| Ethylamine SCHEMBL612047 | 0.76 | TDP1 (0.61) | TDP1ALDH1A1 | |
| SCHEMBL27825520 | 0.75 | — | — | |
| Propylamine SCHEMBL5372435 | 0.75 | TDP1 (0.50) | TDP1MEN1KMT2AALDH1A1 | |
| Ethyl Chloride SCHEMBL28988924 | 0.73 | TDP1 (0.57) | TDP1MEN1KMT2AALDH1A1 | |
| Methylene Chloride SCHEMBL11117712 | 0.73 | TDP1 (0.57) | TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL7868881 | 0.73 | TDP1 (0.57) | TDP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916784-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-04-04 | — | — | CN | disclosed |