Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30385475 | 0.93 | TP53 (0.33) | PTK6 | |
| SCHEMBL22122896 | 0.91 | PTK2 (0.35) | PTK6PTK2TTK | |
| SCHEMBL30384845 | 0.84 | KDM4E (0.37) | PTK2TTK | |
| SCHEMBL25175986 | 0.84 | TP53 (0.35) | PTK6PTK2HTR4 | |
| SCHEMBL30385441 | 0.83 | TP53 (0.39) | PTK2HTR4 | |
| SCHEMBL30386422 | 0.83 | PTK6 (0.33) | PTK6 | |
| SCHEMBL25170406 | 0.82 | PTK6 (0.38) | PTK6TTK | |
| SCHEMBL24870950 | 0.82 | PTK6 (0.36) | PTK6PTK2TTKHTR4HTR3A | |
| SCHEMBL25170404 | 0.82 | JAK2 (0.33) | PTK6TTK | |
| SCHEMBL22123484 | 0.82 | PTK2 (0.38) | PTK6PTK2TTKHTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916784-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-04-04 | — | — | CN | disclosed |