Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 12/20 | 0.61 |
| ▸ | PIK3R1 | P27986 | 9/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.51 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26246729 | 1.00 | PIK3CD (0.61) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL30398158 | 1.00 | PIK3CD (0.61) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL25396153 | 0.91 | PIK3CD (0.52) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL30396632 | 0.91 | PIK3CD (0.52) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL25396151 | 0.91 | PIK3CD (0.52) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL26246743 | 0.86 | PIK3CD (0.48) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL30426165 | 0.86 | PIK3CD (0.48) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL26246747 | 0.86 | PIK3CD (0.48) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL26246712 | 0.83 | PIK3CD (0.51) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| Bosmolisib SCHEMBL20061373 | 0.80 | PIK3CD (0.49) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115968369-A | Process for the preparation of compounds as PI3K inhibitors and intermediate compounds useful for the preparation thereof | 株式会社保宁 | 2023-04-14 | — | — | CN | disclosed |