Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30416067 | 1.00 | ATM (0.59) | ATMMAOAMAOBHDAC3HDAC4 | |
| SCHEMBL8815562 | 0.83 | ATM (0.55) | ATMMAOAMAOBHDAC3HDAC4 | |
| SCHEMBL8813830 | 0.78 | ATM (0.50) | ATMMAOAMAOBHDAC3HDAC4 | |
| SCHEMBL13981288 | 0.77 | ATM (0.59) | ATMMAOAMAOBHDAC3HDAC4 | |
| SCHEMBL27456766 | 0.77 | ATM (0.70) | ATMMAOAMAOBHDAC3HDAC4 | |
| Xanthene Carboxylic Acid SCHEMBL40617 | 0.76 | ATM (0.68) | ATMMAOAMAOBHDAC3HDAC4 | |
| SCHEMBL156372 | 0.76 | ATM (0.68) | ATMMAOAMAOBHDAC3HDAC4 | |
| Xanthene Carboxylic Acid SCHEMBL30011680 | 0.76 | ATM (0.68) | ATMMAOAMAOBHDAC3HDAC4 | |
| Xanthene Carboxylic Acid SCHEMBL9551091 | 0.74 | ATM (0.66) | ATMMAOAMAOBHDAC3HDAC4 | |
| SCHEMBL4777998 | 0.74 | ATM (0.66) | ATMMAOAMAOBHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805277-A | Preparation method of xanthenethioketone compound | 温州大学新材料与产业技术研究院 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805277-A | Preparation method of xanthenethioketone compound | 温州大学新材料与产业技术研究院 | 2022-07-29 | — | — | CN | disclosed |