Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28985178 | 1.00 | MAPT (0.39) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28985190 | 0.81 | HRH4 (0.40) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28985192 | 0.81 | HRH4 (0.40) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30475181 | 0.77 | GRM5 (0.45) | NPC1SMN1; SMN2TP53ALDH1A1LMNA | |
| SCHEMBL30475167 | 0.76 | S1PR2 (0.38) | HDAC6NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28985165 | 0.76 | S1PR2 (0.38) | HDAC6NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28985169 | 0.76 | S1PR2 (0.38) | HDAC6NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12695049 | 0.75 | MAPT (0.46) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL28985166 | 0.75 | GRM5 (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28985164 | 0.75 | GRM5 (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974927-A | Diamine-derived phosphine chiral phosphine oxide ligand-promoted nickel-catalyzed asymmetric alkylation of pyridine C2-H bond | 南开大学 | 2023-04-18 | — | — | CN | disclosed |