Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL28985499 | 1.00 | CYP1A2 (0.52) | CYP1A2LMNAPOLBADORA3ADORA2A | |
| Oxalic Acid SCHEMBL1317140 | 0.97 | CYP1A2 (0.55) | CYP1A2LMNAPOLBADORA3ADORA2A | |
| Oxalic Acid SCHEMBL22468119 | 0.97 | CYP1A2 (0.55) | CYP1A2LMNAPOLBADORA3ADORA2A | |
| Oxalic Acid SCHEMBL30165152 | 0.97 | CYP1A2 (0.55) | CYP1A2LMNAPOLBADORA3ADORA2A | |
| Oxalic Acid SCHEMBL30165185 | 0.97 | CYP1A2 (0.55) | CYP1A2LMNAPOLBADORA3ADORA2A | |
| Oxalic Acid SCHEMBL28322369 | 0.93 | CYP1A2 (0.52) | CYP1A2LMNAPOLBADORA3ADORA2A | |
| Bicarbonate SCHEMBL5708571 | 0.86 | CYP1A2 (0.57) | CYP1A2LMNAPOLBADORA3ADORA2A | |
| Bicarbonate SCHEMBL4615338 | 0.86 | CYP1A2 (0.57) | CYP1A2LMNAPOLBADORA3ADORA2A | |
| Oxalic Acid SCHEMBL11121752 | 0.85 | CYP1A2 (0.46) | CYP1A2LMNAPOLBADORA3ADORA2A | |
| Oxalic Acid SCHEMBL11725826 | 0.85 | CYP1A2 (0.46) | CYP1A2LMNAPOLBADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113490656-B | Cold-fired hydrate fuel in gas generant formulations for automotive airbag applications | 奥托立夫ASP公司 | 2023-04-14 | — | — | CN | disclosed |