Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.96 |
| ▸ | P4HTM | Q9NXG6 | 10/20 | 0.37 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | ASPH | Q12797 | 2/20 | 0.34 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acipimox SCHEMBL6057382 | 0.98 | HCAR2 (1.00) | HCAR2P4HTMP4HA1MIFKDM4E | |
| Acipimox SCHEMBL48922 | 0.98 | HCAR2 (1.00) | HCAR2P4HTMP4HA1MIFKDM4E | |
| Acipimox SCHEMBL29370131 | 0.98 | HCAR2 (1.00) | HCAR2P4HTMP4HA1MIFKDM4E | |
| Acipimox SCHEMBL31290731 | 0.96 | HCAR2 (0.96) | HCAR2P4HTMP4HA1MIFKDM4E | |
| Acipimox SCHEMBL28690337 | 0.96 | HCAR2 (0.96) | HCAR2P4HTMP4HA1MIFKDM4E | |
| Acipimox SCHEMBL28681646 | 0.96 | HCAR2 (0.96) | HCAR2P4HTMP4HA1MIFKDM4E | |
| Acipimox SCHEMBL28273592 | 0.96 | HCAR2 (0.96) | HCAR2P4HTMP4HA1MIFKDM4E | |
| Acipimox SCHEMBL11743417 | 0.87 | HCAR2 (0.79) | HCAR2P4HTMP4HA1MIFKDM4E | |
| Acipimox SCHEMBL28438037 | 0.86 | HCAR2 (0.77) | HCAR2P4HTMP4HA1MIFKDM4E | |
| Acipimox SCHEMBL22409661 | 0.83 | HCAR2 (0.72) | HCAR2P4HTMKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073384-B | Acipimox crystal form and preparation method thereof | 山东新时代药业有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-115073384-A | Acipimox crystal form and preparation method thereof | 山东新时代药业有限公司 | 2022-09-20 | — | — | CN | disclosed |