Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.95 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28987855 | 0.97 | SMN1; SMN2 (1.00) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL28987838 | 0.89 | SMN1; SMN2 (0.80) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL15919093 | 0.86 | SMN1; SMN2 (0.76) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL28987826 | 0.86 | SMN1; SMN2 (0.76) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL15272231 | 0.86 | SMN1; SMN2 (0.76) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL24987981 | 0.86 | SMN1; SMN2 (0.76) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL28987841 | 0.85 | SMN1; SMN2 (0.73) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL28987857 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL28987859 | 0.84 | SMN1; SMN2 (0.72) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL29712398 | 0.83 | SMN1; SMN2 (0.74) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835656-A | 1,3, 4-oxadiazole ethyl acetate and synthesis method thereof | 天津中医药大学 | 2022-08-02 | — | — | CN | disclosed |