Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30415521 | 1.00 | JAK2 (0.36) | JAK2BTKBRD4CCR4CA12 | |
| SCHEMBL30416397 | 0.88 | JAK2 (0.37) | JAK2BTKCCR4CA12CA1 | |
| SCHEMBL15875154 | 0.88 | JAK2 (0.37) | JAK2BTKCCR4CA12CA1 | |
| SCHEMBL28989382 | 0.84 | JAK2 (0.34) | JAK2BTKBRD4CCR4CA12 | |
| SCHEMBL30416083 | 0.84 | JAK2 (0.34) | JAK2BTKBRD4CCR4CA12 | |
| SCHEMBL15995732 | 0.82 | JAK2 (0.33) | JAK2BTKCCR4 | |
| SCHEMBL15995587 | 0.82 | JAK2 (0.38) | JAK2BTK | |
| SCHEMBL15996158 | 0.77 | JAK2 (0.36) | JAK2BTK | |
| SCHEMBL24142870 | 0.76 | BRD4 (0.46) | BRD4CCR4BRDT | |
| SCHEMBL24998323 | 0.76 | CCR4 (0.39) | BRD4CCR4BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996925-A | Capsid inhibitors for the treatment of HIV | 吉利德科学公司 | 2023-04-21 | — | — | CN | disclosed |