SCHEMBL28990232

SCHEMBL28990232

CCCn1ccc2cccc(CC)c21

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.46
GRM2 Q14416 10/20 0.39
OXER1 Q8TDS5 1/20 0.37
CDK4 P11802 3/20 0.37
CCND1 P24385 3/20 0.37
GABRA1 P14867 2/20 0.36
GABRB2 P47870 2/20 0.36
CNR2 P34972 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15676807 0.85 BACE1 (0.48) BACE1OXER1CDK4CCND1GABRA1
SCHEMBL5446561 0.83 BACE1 (0.45) BACE1OXER1CDK4CCND1GABRA1
SCHEMBL11005480 0.79 CMA1 (0.48) BACE1OXER1CDK4CCND1GABRA1
SCHEMBL12384269 0.79 SLC6A4 (0.39) GRM2CDK4CCND1CNR2
SCHEMBL1696643 0.78 APP (0.50) BACE1
SCHEMBL28990233 0.78 OXER1 (0.46) BACE1OXER1CDK4CCND1CNR2
SCHEMBL14397085 0.77 BACE1 (0.45) BACE1OXER1GABRA1GABRB2
SCHEMBL28577320 0.76 CDK4 (0.39) BACE1GRM2CDK4CCND1CNR2
SCHEMBL6085455 0.76 BACE1 (0.47) BACE1
SCHEMBL1696888 0.75 OXER1 (0.40) BACE1OXER1CDK4CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115838348-B Synthesis method and application of benzopyrrole quaternary ammonium base 万华化学集团股份有限公司 2024-11-12 CN disclosed
CN-115838348-A Synthetic method and application of benzopyrrole quaternary ammonium hydroxide 万华化学集团股份有限公司 2023-03-24 CN disclosed