SCHEMBL28990983

SCHEMBL28990983

C#Cc1ccc(OC)cn1.C#Cc1ccc(OC)cn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 3/20 0.43
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
GRM5 P41594 2/20 0.39
ACACB O00763 1/20 0.38
NQO1 P15559 1/20 0.37
TUBB4A P04350 1/20 0.37
TUBB P07437 1/20 0.37
TUBA3C P0DPH7 1/20 0.37
TUBA1B P68363 1/20 0.37
TUBA4A P68366 1/20 0.37
TUBB4B P68371 1/20 0.37
TUBB3 Q13509 1/20 0.37
TUBB2A Q13885 1/20 0.37
TUBB8 Q3ZCM7 1/20 0.37
TUBA3E Q6PEY2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13527880 1.00 PDE2A (0.43) PDE2ACA12CA1CA2CA7
SCHEMBL256035 0.85 MCHR1 (0.49) PDE2ACA12CA1CA2CA7
SCHEMBL17141754 0.83 PDE2A (0.58) PDE2AMAPTALDH1A1
SCHEMBL240556 0.81 NQO1 (0.50) CA12CA1CA2CA7CA9
SCHEMBL1391688 0.80 NQO1 (0.48) CA12CA1CA2CA7CA9
SCHEMBL17980663 0.80 EGFR (0.38) PDE2AGRM5EGFR
SCHEMBL256100 0.79 ACACB (0.43) GRM5ACACBKMT2AALDH1A1
SCHEMBL23704219 0.78 ACACB (0.43) CA12CA1CA2CA7CA9
SCHEMBL30078388 0.78 ACACB (0.43) CA12CA1CA2CA7CA9
SCHEMBL21535959 0.76 ACACB (0.42) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115867525-A Improvements in and relating to nitrification inhibitors 林肯大学 2023-03-28 CN disclosed