Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 11/20 | 0.72 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | GOT1 | P17174 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30386673 | 1.00 | STING1 (0.72) | STING1MTOREPHX2GOT1MEN1 | |
| SCHEMBL22803837 | 0.91 | STING1 (0.77) | STING1MTOREPHX2GOT1MEN1 | |
| SCHEMBL23206890 | 0.90 | STING1 (0.58) | STING1MTOREPHX2GOT1 | |
| SCHEMBL23207919 | 0.88 | STING1 (0.60) | STING1MTOREPHX2GOT1 | |
| SCHEMBL23208193 | 0.88 | STING1 (0.65) | STING1MTOREPHX2GOT1MEN1 | |
| SCHEMBL23167133 | 0.87 | STING1 (0.70) | STING1MTOREPHX2GOT1MEN1 | |
| SCHEMBL30885411 | 0.87 | STING1 (0.70) | STING1MTOREPHX2GOT1MEN1 | |
| SCHEMBL22803694 | 0.86 | STING1 (0.69) | STING1MTOREPHX2GOT1MEN1 | |
| SCHEMBL23207917 | 0.85 | STING1 (0.65) | STING1MTOREPHX2GOT1MEN1 | |
| SCHEMBL30195938 | 0.85 | STING1 (0.65) | STING1MTOREPHX2GOT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116023321-A | STING inhibitor prodrug and medical application thereof | 中国药科大学 | 2023-04-28 | — | — | CN | disclosed |