⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322429 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28671037 | 0.98 | CACNA2D1 (0.59) | — | |
| SCHEMBL13679351 | 0.89 | CACNA2D1 (0.67) | — | |
| Hydrochloric Acid SCHEMBL29021000 | 0.87 | CACNA2D1 (0.64) | — | |
| SCHEMBL276400 | 0.87 | — | — | |
| SCHEMBL24653140 | 0.84 | CACNA2D1 (0.65) | — | |
| SCHEMBL804682 | 0.84 | CACNA2D1 (0.46) | — | |
| SCHEMBL11761433 | 0.84 | CACNA2D1 (0.46) | — | |
| SCHEMBL7907883 | 0.84 | — | — | |
| SCHEMBL27936230 | 0.84 | CACNA2D1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850240-A | Synthetic method of drug Olutascinonide for treating acute myeloid leukemia | 北京康立生医药技术开发有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115850240-A | Synthetic method of drug Olutascinonide for treating acute myeloid leukemia | 北京康立生医药技术开发有限公司 | 2023-03-28 | — | — | CN | disclosed |