Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.45 |
| ▸ | BTK | Q06187 | 11/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.44 |
| ▸ | CDK9 | P50750 | 4/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289738 | 0.93 | CCNT1 (0.46) | EGFRBTKCCNT1CDK9 | |
| SCHEMBL30289735 | 0.93 | BTK (0.45) | EGFRBTKCCNT1CDK9 | |
| SCHEMBL30289593 | 0.92 | BTK (0.44) | EGFRBTKCCNT1CDK9 | |
| SCHEMBL30289638 | 0.92 | BTK (0.44) | EGFRBTKCCNT1CDK9 | |
| SCHEMBL30289630 | 0.89 | EGFR (0.44) | EGFRBTKCCNT1CDK9 | |
| SCHEMBL30289579 | 0.88 | BTK (0.48) | EGFRBTKMET | |
| SCHEMBL28994189 | 0.86 | BTK (0.46) | EGFRBTKMET | |
| SCHEMBL30289723 | 0.86 | MAPK1 (0.49) | EGFRBTKKITMET | |
| SCHEMBL30289655 | 0.86 | EGFR (0.47) | EGFRBTKMET | |
| SCHEMBL30289572 | 0.85 | EGFR (0.54) | EGFRBTKMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894497-A | Imidazopyrimidine compounds, and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-04-04 | — | — | CN | disclosed |