Tetrabutyhydroxytoluene

Tetrabutyhydroxytoluene

SCHEMBL2899487

CCCCc1c(C)c(O)c(CCCC)c(CCCC)c1CCCC

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.45
NPC1 O15118 1/20 0.45
MAPK1 P28482 1/20 0.45
HTT P42858 1/20 0.45
RAB9A P51151 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
FFAR1 O14842 1/20 0.40
TYR P14679 1/20 0.38
KDM4E B2RXH2 2/20 0.37
PKM P14618 1/20 0.37
CYP19A1 P11511 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PLA2G2A P14555 1/20 0.35
PLA2G5 P39877 1/20 0.35
ALOX5 P09917 4/20 0.35
CFTR P13569 4/20 0.35
FASN P49327 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27797480 0.93 HPGD (0.43) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL28454033 0.93 HPGD (0.43) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL27929167 0.89 HPGD (0.41) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL27993622 0.88 HPGD (0.43) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL5586620 0.87 HPGD (0.50) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL268313 0.87 HPGD (0.50) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL29311921 0.85 HPGD (0.45) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL17666984 0.85 HPGD (0.45) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL28029522 0.84 AKR1B1 (0.42) FFAR1ALDH1A1HSD17B10
SCHEMBL27957020 0.84 HPGD (0.48) HPGDNPC1MAPK1HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481466-B2 Soybean, canola oil lubricating base oil; lithium soap, urea, aluminum complex soap, bentonite thickener; polymethacrylate pour point depressant; dithiocarbamate lubricating additive; ethylene propylene structure stabilizer; tetrabutyl methylphenol oxidation inhibitor; benzotriazole corrosion inhibitor KOREA HOUGHTON CORPORATION (KR) 2013-07-09 US claimed
EP-1944352-B1 Biodegradable grease composition using distillation residue generated in production of biodiesel KOREA HOUGHTON CORP (KR) 2010-08-11 EP claimed
US-20080171676-A1 Biodegradable grease composition using distillation residue generated in production of biodiesel KOREA HOUGHTON CORPORATION (KR) 2008-07-17 US claimed
EP-1944352-A1 Biodegradable grease composition using distillation residue generated in production of biodiesel Korea Houghton Corporation (KR) 2008-07-16 EP claimed
CN-1317370-C Diesel IC engine environmental protection fuel composition and its fuel conveying system XINDONGLI FUEL DEV CO LTD (CN) 2007-05-23 CN claimed
CN-1424382-A Diesel IC engine environmental protection fuel composition and its fuel conveying system XINDONGLI FUEL DEV CO LTD (CN) 2003-06-18 CN claimed
CN-106456526-A Cosmetic composition for skin whitening and wrinkle alleviation, containing, as active ingredients, white rose extract and gartanin derivative compound isolated therefrom 忠北大学校产学协力团 2017-02-22 CN disclosed
US-8481466-B2 Soybean, canola oil lubricating base oil; lithium soap, urea, aluminum complex soap, bentonite thickener; polymethacrylate pour point depressant; dithiocarbamate lubricating additive; ethylene propylene structure stabilizer; tetrabutyl methylphenol oxidation inhibitor; benzotriazole corrosion inhibitor KOREA HOUGHTON CORPORATION (KR) 2013-07-09 US disclosed
EP-1944352-B1 Biodegradable grease composition using distillation residue generated in production of biodiesel KOREA HOUGHTON CORP (KR) 2010-08-11 EP disclosed
US-20080171676-A1 Biodegradable grease composition using distillation residue generated in production of biodiesel KOREA HOUGHTON CORPORATION (KR) 2008-07-17 US disclosed
EP-1944352-A1 Biodegradable grease composition using distillation residue generated in production of biodiesel Korea Houghton Corporation (KR) 2008-07-16 EP disclosed
CN-1317370-C Diesel IC engine environmental protection fuel composition and its fuel conveying system XINDONGLI FUEL DEV CO LTD (CN) 2007-05-23 CN disclosed
CN-1965065-A Odorizing mixture for an odorless gas fuel ARKEMA (FR) 2007-05-16 CN disclosed
CN-1424382-A Diesel IC engine environmental protection fuel composition and its fuel conveying system XINDONGLI FUEL DEV CO LTD (CN) 2003-06-18 CN disclosed