Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI2 | P48307 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22032663 | 0.78 | TFPI2 (0.32) | TFPI2 | |
| SCHEMBL22032719 | 0.78 | TFPI2 (0.32) | TFPI2 | |
| SCHEMBL1220092 | 0.78 | TFPI2 (0.32) | TFPI2 | |
| SCHEMBL504856 | 0.75 | TFPI2 (0.30) | TFPI2 | |
| SCHEMBL30009419 | 0.71 | ACE (0.33) | — | |
| SCHEMBL142200 | 0.69 | — | — | |
| SCHEMBL1219788 | 0.68 | CHRM2 (0.32) | — | |
| SCHEMBL28536100 | 0.67 | — | — | |
| SCHEMBL19582825 | 0.67 | TFPI2 (0.33) | TFPI2 | |
| SCHEMBL14480018 | 0.64 | DPP4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901277-A | Isoindolinone and indazole compounds for EGFR degradation | C4医药公司 | 2022-08-12 | — | — | CN | disclosed |