Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 2/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | UGCG | Q16739 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30491809 | 1.00 | PPARA (0.50) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL25807391 | 1.00 | PPARA (0.50) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL30491806 | 0.91 | PPARA (0.48) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL28995593 | 0.91 | PPARA (0.48) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL25807459 | 0.91 | PPARA (0.48) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL28995695 | 0.89 | ATM (0.53) | CTSSKLK5ATMAAK1CTSB | |
| SCHEMBL25811463 | 0.89 | ATM (0.53) | CTSSKLK5ATMAAK1CTSB | |
| SCHEMBL25291935 | 0.87 | UGCG (0.42) | UGCG | |
| SCHEMBL25252573 | 0.87 | UGCG (0.42) | UGCG | |
| SCHEMBL30491783 | 0.86 | PPARA (0.49) | PPARACTSSPPARGKLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916790-A | Pyrido [2,3-b ] [1,4] oxazines or tetrahydropyrido [2,3-b ] [1,4] oxazepines as IAP antagonists | 百济神州有限公司 | 2023-04-04 | — | — | CN | disclosed |