Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28995642 | 0.89 | SCN9A (0.41) | SCN9AAAK1 | |
| SCHEMBL28995606 | 0.85 | AAK1 (0.40) | SCN9AAAK1 | |
| SCHEMBL28995676 | 0.84 | HDAC8 (0.38) | CTSKCTSLCTSBHDAC8 | |
| SCHEMBL28995674 | 0.84 | HDAC8 (0.38) | CTSKCTSLCTSBHDAC8 | |
| SCHEMBL28995594 | 0.83 | AAK1 (0.43) | SCN9AAAK1 | |
| SCHEMBL28995589 | 0.81 | UGCG (0.40) | SCN9AAAK1 | |
| SCHEMBL28995695 | 0.78 | ATM (0.53) | CTSKCTSLCTSBAAK1 | |
| SCHEMBL25811463 | 0.78 | ATM (0.53) | CTSKCTSLCTSBAAK1 | |
| SCHEMBL28995634 | 0.77 | AAK1 (0.38) | SCN9AAAK1MEN1KMT2A | |
| SCHEMBL28995562 | 0.77 | AAK1 (0.37) | SCN9AAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916790-A | Pyrido [2,3-b ] [1,4] oxazines or tetrahydropyrido [2,3-b ] [1,4] oxazepines as IAP antagonists | 百济神州有限公司 | 2023-04-04 | — | — | CN | disclosed |