Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | UGCG | Q16739 | 3/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 3/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28995777 | 1.00 | PLAU (0.39) | PLAUUGCGPSMB5SLC6A4SLC1A1 | |
| SCHEMBL28995589 | 0.84 | UGCG (0.40) | UGCGPSMB5PPARA | |
| SCHEMBL28995561 | 0.81 | SLC1A1 (0.36) | SLC1A1TACR1 | |
| SCHEMBL28995559 | 0.81 | SLC1A1 (0.36) | SLC1A1TACR1 | |
| SCHEMBL25296455 | 0.80 | UGCG (0.41) | PLAUUGCGPSMB5SLC6A4THRA | |
| SCHEMBL25252120 | 0.80 | UGCG (0.41) | PLAUUGCGPSMB5SLC6A4THRA | |
| SCHEMBL28995590 | 0.79 | CYP1A2 (0.36) | — | |
| SCHEMBL28995592 | 0.79 | CYP1A2 (0.36) | — | |
| SCHEMBL28995676 | 0.77 | HDAC8 (0.38) | PSMB5THRATHRBPPARA | |
| SCHEMBL28995674 | 0.77 | HDAC8 (0.38) | PSMB5THRATHRBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916790-A | Pyrido [2,3-b ] [1,4] oxazines or tetrahydropyrido [2,3-b ] [1,4] oxazepines as IAP antagonists | 百济神州有限公司 | 2023-04-04 | — | — | CN | disclosed |