Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 6/20 | 0.69 |
| ▸ | EZH1 | Q92800 | 9/20 | 0.60 |
| ▸ | EED | O75530 | 2/20 | 0.60 |
| ▸ | RBBP4 | Q09028 | 2/20 | 0.60 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.60 |
| ▸ | RBBP7 | Q16576 | 2/20 | 0.60 |
| ▸ | AEBP2 | Q6ZN18 | 2/20 | 0.60 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.57 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28995997 | 0.95 | EZH2 (0.69) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL28996183 | 0.93 | EZH2 (0.71) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL28995941 | 0.93 | EZH2 (0.67) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL28996007 | 0.90 | EZH2 (0.67) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL28995994 | 0.89 | EZH2 (0.87) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL28996065 | 0.88 | EZH2 (0.60) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL30123418 | 0.87 | EZH2 (0.82) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL21271624 | 0.87 | EZH2 (0.82) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL28996059 | 0.86 | EZH2 (0.68) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL28996004 | 0.86 | EZH2 (0.65) | EZH2EZH1EEDRBBP4SUZ12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082320-A | ZESTE enhancer homolog 2 inhibitors and uses thereof | 海思科医药集团股份有限公司 | 2023-05-09 | — | — | CN | disclosed |