Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 9/20 | 0.41 |
| ▸ | SRC | P12931 | 5/20 | 0.41 |
| ▸ | ZAP70 | P43403 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30252976 | 1.00 | HSP90AA1 (0.47) | HSP90AA1SYKSRCZAP70KDM4E | |
| SCHEMBL24774090 | 0.87 | DYRK1A (0.35) | KDM4EALDH1A1LMNAHPGDEGFR | |
| SCHEMBL29290793 | 0.84 | HSP90AA1 (0.48) | HSP90AA1SYKSRCZAP70CDK2 | |
| SCHEMBL30252756 | 0.80 | ADORA2A (0.42) | HSP90AA1SYKSRCZAP70KDM4E | |
| SCHEMBL20911605 | 0.80 | ADORA2A (0.42) | HSP90AA1SYKSRCZAP70KDM4E | |
| SCHEMBL30252762 | 0.80 | HSP90AA1 (0.42) | HSP90AA1SYKSRCZAP70CDK2 | |
| SCHEMBL20911603 | 0.80 | HSP90AA1 (0.42) | HSP90AA1SYKSRCZAP70CDK2 | |
| SCHEMBL30252529 | 0.78 | HSP90AA1 (0.56) | HSP90AA1SYKSRCZAP70ALDH1A1 | |
| SCHEMBL30252663 | 0.77 | HSP90AA1 (0.49) | HSP90AA1SYKSRCZAP70LMNA | |
| SCHEMBL29290796 | 0.77 | HSP90AA1 (0.42) | HSP90AA1SYKSRCZAP70CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651358-B | 4-aminopyridine derivative, pharmaceutical composition, preparation method and application thereof | 上海迪诺医药科技有限公司 | 2023-04-07 | — | — | CN | disclosed |