Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.39 |
| ▸ | CA2 | P00918 | 10/20 | 0.39 |
| ▸ | CA9 | Q16790 | 8/20 | 0.39 |
| ▸ | CA12 | O43570 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20398730 | 1.00 | CA1 (0.39) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL28997378 | 1.00 | CA1 (0.39) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL20398753 | 1.00 | CA1 (0.39) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL20398721 | 1.00 | CA1 (0.39) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL20444259 | 0.84 | CA1 (0.35) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL22503762 | 0.84 | KMT2A (0.43) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL21880804 | 0.84 | CA1 (0.35) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL20424215 | 0.84 | KMT2A (0.43) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL20442243 | 0.84 | KMT2A (0.43) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL20398734 | 0.84 | KMT2A (0.43) | CA1CA2CA9CA12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110248929-B | Benzyl amino pyrazinyl cyclopropanecarboxylic acid, pharmaceutical composition and use thereof | 勃林格殷格翰国际有限公司 | 2023-05-12 | — | — | CN | disclosed |