Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30352432 | 1.00 | MKNK1 (0.33) | MKNK1TBK1BTK | |
| SCHEMBL28998194 | 0.87 | AAK1 (0.35) | MKNK1BTK | |
| SCHEMBL28998255 | 0.83 | BACE1 (0.33) | MKNK1BTK | |
| SCHEMBL28998213 | 0.82 | BTK (0.35) | BTK | |
| SCHEMBL28998240 | 0.81 | BACE1 (0.32) | BTK | |
| SCHEMBL28998733 | 0.79 | BACE1 (0.39) | BTK | |
| SCHEMBL28998266 | 0.79 | — | — | |
| SCHEMBL28998149 | 0.78 | — | — | |
| SCHEMBL28998169 | 0.78 | GSK3B (0.37) | — | |
| SCHEMBL28998163 | 0.74 | ATM (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115942972-A | LPA receptor antagonists and uses thereof | 吉利德科学公司 | 2023-04-07 | — | — | CN | disclosed |