Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ciprofloxacin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | TOP2A | P11388 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | TOP2B | Q02880 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | BRD4 | O60885 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.62 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.62 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.62 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ciprofloxacin SCHEMBL2325956 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Ciprofloxacin SCHEMBL29137332 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Ciprofloxacin SCHEMBL4459712 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Ciprofloxacin SCHEMBL345730 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Ciprofloxacin SCHEMBL7994990 | 0.99 | KDM4E (0.98) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Ciprofloxacin SCHEMBL2465661 | 0.99 | KDM4E (0.98) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Ciprofloxacin SCHEMBL1973497 | 0.99 | KDM4E (0.98) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Ciprofloxacin SCHEMBL21519294 | 0.99 | KDM4E (0.98) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Ciprofloxacin SCHEMBL42310 | 0.99 | KDM4E (0.98) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Ciprofloxacin SCHEMBL5618780 | 0.99 | KDM4E (0.98) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 111480 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260145984-A1 | EXPANDING TIP PLUGS AND METHOD OF USING AND MAKING THE SAME | CORNING INCORPORATED (US) | 2026-05-28 | — | — | US | claimed |
| EP-4113688-B1 | SULFIDE SOLID ELECTROLYTE FOR ALL-SOLID SECONDARY BATTERY, METHOD OF PREPARING THE SAME, AND ALL-SOLID SECONDARY BATTERY INCLUDING THE SAME | SAMSUNG SDI CO LTD (KR) | 2026-05-27 | — | — | EP | claimed |
| EP-3802484-B1 | DOPED METAL HALIDE PEROVSKITES WITH IMPROVED STABILITY AND SOLAR CELLS COMPRISING SAME | GOVERNING COUNCIL UNIV TORONTO (CA) | 2026-05-27 | — | — | EP | claimed |
| EP-4749288-A1 | COMPOSITIONS FOR DETECTING, CHARACTERIZING, AND REMOVING A BIOFILM | COSA Group GmbH (DE) | 2026-05-27 | — | — | EP | claimed |
| CN-122076465-A | Supported ternary heterojunction photocatalytic material and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075390-A | Preparation and application of novel cow uterus injectant | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075719-A | Neuraminidase-ROS dual-response nano-carrier as well as preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122076460-A | Metal doped bismuth ferrite based perovskite composite material and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122094963-A | Cardioprotective lipids and methods of use | — | 2026-05-26 | — | — | CN | claimed |
| WO-2026106551-A1 | ANTIMICROBIAL PEPTIDE NANONETS AND METHODS OF USE THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2026-05-21 | — | — | WO | claimed |
| WO-1986006630-A1 | USE OF QUINOLONE DERIVATIVES FOR THE TREATMENT OF MYCOPLASMAL PNEUMONIA IN PIGS | BEECHAM GROUP P.L.C. (GB) | 1986-11-20 | — | — | WO | claimed |
| EP-0078362-B1 | 1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-PIPERAZINO-QUINOLINE-3-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS CONTAINING THEM | BAYER AG (DE) | 1986-10-22 | — | — | EP | claimed |
| EP-0187315-A2 | Basic quinolonecarboxylic-acid preparations | BAYER AG (DE) | 1986-07-16 | — | — | EP | claimed |
| US-4599334-A | 7-(3-aryl-1-piperazinyl)- and 7-(3-cyclohexyl-1-piperazinyl)-3-quinolonecarboxylic acid antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1986-07-08 | — | — | US | claimed |
| US-4563459-A | FUNGICIDES AND BACTERICIDES FOR AGRICULTURAL USE | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | claimed |
| EP-0165474-A1 | Immunostimulant agent | BAYER AG (DE) | 1985-12-27 | — | — | EP | claimed |
| EP-0138018-A2 | Solutions of lactic acid salts of piperazinylquinolone and piperazinyl azaquinolonecarboxylic acids | BAYER AG (DE) | 1985-04-24 | — | — | EP | claimed |
| EP-0049355-B1 | 7-Amino-1-cyclopropyl-4-oxo-1,4-dihydro-(naphthyridine or quinoline)-3-carboxylic acids, process for their preparation and pharmaceutical compositions containing them | BAYER AG (DE) | 1984-10-10 | — | — | EP | claimed |
| EP-0078362-A2 | 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-quinoline-3-carboxylic acids, process for their preparation and antibacterial agents containing them | BAYER AG (DE) | 1983-05-11 | — | — | EP | claimed |
| EP-0049355-A1 | 7-Amino-1-cyclopropyl-4-oxo-1,4-dihydro-(naphthyridine or quinoline)-3-carboxylic acids, process for their preparation and pharmaceutical compositions containing them | BAYER AG (DE) | 1982-04-14 | — | — | EP | claimed |