Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL6572045 | 0.87 | FFAR3 (0.43) | — | |
| Carbamic Acid SCHEMBL9671042 | 0.85 | — | — | |
| SCHEMBL9397438 | 0.85 | — | — | |
| SCHEMBL16240342 | 0.83 | — | — | |
| Bicarbonate SCHEMBL10711598 | 0.82 | FFAR3 (0.45) | — | |
| SCHEMBL11900984 | 0.77 | FFAR3 (0.40) | — | |
| Bicarbonate SCHEMBL29746467 | 0.77 | — | — | |
| Acetic Acid SCHEMBL4357455 | 0.77 | FFAR3 (0.41) | — | |
| SCHEMBL4867997 | 0.77 | FFAR3 (0.82) | — | |
| Bicarbonate SCHEMBL10668252 | 0.77 | FFAR3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1489066-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE CARBOXYLIC ACID | AJINOMOTO KK (JP) | 2010-08-04 | — | — | EP | claimed |
| EP-0524604-B1 | Process for the preparations of S-(+)-2,2-dimethyl-cyclopropane carboxamid by genetically engineered microorganismes | LONZA AG (CH) | 1998-10-14 | — | — | EP | claimed |
| EP-0502525-B1 | Biotechnological process for the production of S-(+)-2,2-dimethylcyclopropanecarboxamide and R-(-)-2,2-dimethylcyclopropanecarboxylic acid | LONZA AG (CH) | 1996-06-26 | — | — | EP | claimed |
| EP-0491330-B1 | Process for the preparation of dimethylcyclopropancarboxylic acid | LONZA AG (CH) | 1995-03-22 | — | — | EP | claimed |
| EP-0474200-B1 | Process for the resolution of racemic 2,2-dimethyl cyclopropane carboxylic acid | LONZA AG (CH) | 1994-12-14 | — | — | EP | claimed |
| EP-0461541-B1 | Process for the resolution of 2,2-dimethylcyclopropane carboxylic acid racemate | LONZA AG (CH) | 1994-12-14 | — | — | EP | claimed |
| EP-0524604-A2 | Process for the preparations of S-(+)-2,2-dimethyl-cyclopropane carboxamid by genetically engineered microorganismes | LONZA A.G. (CH) | 1993-01-27 | — | — | EP | claimed |
| EP-0502525-A1 | Biotechnological process for the production of S-(+)-2,2-dimethylcyclopropanecarboxamide and R-(-)-2,2-dimethylcyclopropanecarboxylic acid | LONZA AG (CH) | 1992-09-09 | — | — | EP | claimed |
| EP-0491330-A1 | Process for the preparation of dimethylcyclopropancarboxylic acid | LONZA AG (CH) | 1992-06-24 | — | — | EP | claimed |
| EP-0474200-A2 | Process for the resolution of racemic 2,2-dimethyl cyclopropane carboxylic acid | LONZA AG (CH) | 1992-03-11 | — | — | EP | claimed |
| EP-0461541-A2 | Process for the resolution of 2,2-dimethylcyclopropane carboxylic acid racemate | LONZA AG (CH) | 1991-12-18 | — | — | EP | claimed |
| EP-0155779-B1 | A METHOD FOR THE OPTICAL PURIFICATION OF AN OPTICALLY ACTIVE 2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID AMIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-04-26 | — | — | EP | claimed |
| EP-0134303-B1 | MENTHYL 2,2-DIMETHYLCYCLOPROPANECARBOXYLATE AND RESOLUTION OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-01-27 | — | — | EP | claimed |
| EP-0093511-B1 | METHOD FOR PRODUCING AND OPTICALLY ACTIVE 2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-09-24 | — | — | EP | claimed |
| CN-107004845-B | Negative active material for secondary battery and secondary battery using the same | 日进电气有限公司 | 2020-01-31 | — | — | CN | disclosed |
| EP-0835860-B1 | Process for the preparation of esters or alcoholates by water separation | BAYER AG (DE) | 2001-06-13 | — | — | EP | disclosed |
| EP-0524604-B1 | Process for the preparations of S-(+)-2,2-dimethyl-cyclopropane carboxamid by genetically engineered microorganismes | LONZA AG (CH) | 1998-10-14 | — | — | EP | disclosed |
| EP-0258815-A2 | Derivatives of 2,2-dimethyl-cyclopropanecarboxylic acid | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1988-03-09 | — | — | EP | disclosed |
| EP-0006205-B1 | PROCESS FOR THE PREPARATION OF CHLOROSTYRENECYCLOPROPANE CARBOXYLIC ACID DERIVATIVES | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |
| EP-0006205-A1 | Process for the preparation of chlorostyrenecyclopropane carboxylic acid derivatives | BAYER AG (DE) | 1980-01-09 | — | — | EP | disclosed |