Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29000800 | 1.00 | KMT2A (0.50) | KMT2AALDH1A1KDM4EGAANPSR1 | |
| SCHEMBL21796797 | 0.82 | KDM4E (0.44) | KMT2AALDH1A1KDM4EGAANPSR1 | |
| SCHEMBL21797060 | 0.82 | KDM4E (0.44) | KMT2AALDH1A1KDM4EGAANPSR1 | |
| SCHEMBL18399046 | 0.82 | LRRK2 (0.41) | KMT2ALMNAHRH4LRRK2 | |
| SCHEMBL26604079 | 0.81 | KMT2A (0.55) | KMT2AALDH1A1KDM4EGAANPSR1 | |
| SCHEMBL26604101 | 0.81 | KMT2A (0.55) | KMT2AALDH1A1KDM4EGAANPSR1 | |
| SCHEMBL25141999 | 0.81 | HRH4 (0.39) | LMNAHRH4LRRK2 | |
| SCHEMBL20905952 | 0.81 | HRH4 (0.39) | LMNAHRH4LRRK2 | |
| SCHEMBL23554796 | 0.79 | LRRK2 (0.47) | LMNAHRH4LRRK2 | |
| SCHEMBL18399090 | 0.76 | CYP1A2 (0.60) | KMT2AALDH1A1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120291-B | Indazole compound, preparation method and application thereof | 英矽智能科技(上海)有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116120291-A | Indazole compound, preparation method and application thereof | 英矽智能科技(上海)有限公司 | 2023-05-16 | — | — | CN | disclosed |