Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 20/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | KRAS | P01116 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29002570 | 0.92 | SOS1 (0.56) | SOS1EGFRKRAS | |
| SCHEMBL23520562 | 0.82 | SOS1 (0.68) | SOS1EGFRKRAS | |
| SCHEMBL20327096 | 0.79 | SOS1 (0.65) | SOS1EGFRKRAS | |
| SCHEMBL30455241 | 0.79 | SOS1 (0.65) | SOS1EGFRKRAS | |
| SCHEMBL29002552 | 0.79 | SOS1 (0.65) | SOS1EGFRKRAS | |
| SCHEMBL23520563 | 0.78 | SOS1 (0.62) | SOS1EGFRKRAS | |
| SCHEMBL20327631 | 0.78 | SOS1 (0.62) | SOS1EGFRKRAS | |
| SCHEMBL24576525 | 0.77 | GALR3 (0.58) | SOS1EGFRKRAS | |
| SCHEMBL24576519 | 0.77 | GALR3 (0.58) | SOS1EGFRKRAS | |
| SCHEMBL29775101 | 0.77 | GALR3 (0.58) | SOS1EGFRKRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143708-A | Polysubstituted benzazepine heteroaryl derivative and application thereof | 四川汇宇制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |