Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 12/20 | 0.42 |
| ▸ | GRM5 | P41594 | 4/20 | 0.42 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 7/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29002681 | 0.84 | MAP2K7 (0.41) | BTKMAP2K7TGM2EGFRKCNH2 | |
| SCHEMBL29002663 | 0.80 | MAP2K7 (0.43) | BTKMAP2K7TGM2EGFRKCNH2 | |
| SCHEMBL31745489 | 0.79 | BTK (0.41) | BTKMAP2K7TGM2EGFRKCNH2 | |
| SCHEMBL31745484 | 0.79 | BTK (0.41) | BTKMAP2K7TGM2EGFRKCNH2 | |
| SCHEMBL30736056 | 0.79 | EGFR (0.40) | BTKMAP2K7TGM2EGFR | |
| SCHEMBL31745539 | 0.79 | BTK (0.40) | BTKMAP2K7TGM2EGFRKCNH2 | |
| SCHEMBL31745486 | 0.79 | BTK (0.40) | BTKMAP2K7TGM2EGFRKCNH2 | |
| SCHEMBL31745444 | 0.79 | BTK (0.41) | BTKMAP2K7TGM2EGFRKCNH2 | |
| SCHEMBL31745485 | 0.79 | BTK (0.42) | BTKMAP2K7TGM2EGFRKCNH2 | |
| SCHEMBL22676078 | 0.78 | FGFR1 (0.51) | BTKMAP2K7EGFRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115772161-A | Nitrogen-containing heteroaryl compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-03-10 | — | — | CN | disclosed |