Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2903547 | 0.85 | MTOR (1.00) | MTOR | |
| SCHEMBL10224930 | 0.84 | MTOR (1.00) | MTOR | |
| SCHEMBL2925208 | 0.84 | MTOR (1.00) | MTOR | |
| SCHEMBL4172225 | 0.83 | MTOR (1.00) | MTOR | |
| SCHEMBL2900196 | 0.83 | MTOR (1.00) | MTOR | |
| SCHEMBL2906195 | 0.83 | MTOR (1.00) | MTOR | |
| SCHEMBL393909 | 0.83 | MTOR (0.83) | MTOR | |
| SCHEMBL393908 | 0.83 | MTOR (0.83) | MTOR | |
| SCHEMBL2900427 | 0.83 | MTOR (1.00) | MTOR | |
| SCHEMBL2900697 | 0.81 | MTOR (1.00) | MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217234-A2 | COMBINATIONS OF MEK INHIBITORS WITH MTOR INHIBITORS | AstraZeneca AB (SE) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009050506-A2 | COMBINATION 059 | ASTRAZENECA AB (SE) | 2009-04-23 | — | — | WO | disclosed |