Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 4/20 | 0.53 |
| ▸ | ANO1 | Q5XXA6 | 11/20 | 0.48 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.45 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.45 |
| ▸ | RORA | P35398 | 1/20 | 0.44 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29005443 | 0.91 | P2RX4 (0.62) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL30285710 | 0.89 | P2RX4 (0.61) | P2RX4ANO1RORANR2E1 | |
| SCHEMBL26186535 | 0.89 | P2RX4 (0.61) | P2RX4ANO1RORANR2E1 | |
| SCHEMBL29005405 | 0.88 | P2RX4 (0.53) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL26186569 | 0.86 | P2RX4 (0.63) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL29005473 | 0.85 | P2RX4 (0.62) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL26186539 | 0.84 | P2RX4 (0.61) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL30285805 | 0.84 | P2RX4 (0.61) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL25371065 | 0.83 | P2RX4 (0.69) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL29005387 | 0.83 | P2RX4 (0.67) | P2RX4ANO1KCNJ5KCNJ3RORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | claimed |