Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10743523 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAMAPK1P2RX4BCHE | |
| SCHEMBL21722352 | 0.78 | NR1H2 (0.32) | ALDH1A1 | |
| SCHEMBL2204621 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAMAPK1P2RX4BCHE | |
| SCHEMBL2314921 | 0.75 | P2RX4 (0.40) | SMN1; SMN2LMNAMAPK1P2RX4ALDH1A1 | |
| SCHEMBL38664533 | 0.75 | P2RX4 (0.40) | SMN1; SMN2LMNAMAPK1P2RX4ALDH1A1 | |
| Propionic Acid SCHEMBL31424601 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAMAPK1P2RX4BCHE | |
| SCHEMBL27473378 | 0.73 | BCHE (0.49) | SMN1; SMN2LMNAMAPK1P2RX4BCHE | |
| SCHEMBL28644142 | 0.72 | P2RX4 (0.38) | SMN1; SMN2P2RX4MEN1KMT2AP2RX1 | |
| SCHEMBL18153249 | 0.69 | SMN1; SMN2 (0.68) | SMN1; SMN2LMNAMAPK1P2RX4BCHE | |
| SCHEMBL11412073 | 0.66 | P2RX4 (0.71) | SMN1; SMN2LMNAMAPK1P2RX4BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115957338-A | High-stability targeting joint-drug conjugate | 成都科岭源医药技术有限公司 | 2023-04-14 | — | — | CN | disclosed |