SCHEMBL29007902

SCHEMBL29007902

O=C(O)N1CCCC1COc1ncccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 1/20 0.44
CHRNB4 P30926 2/20 0.44
CHRNA3 P32297 2/20 0.44
LTA4H P09960 4/20 0.40
CHRNB1 P11230 1/20 0.40
CHRNB2 P17787 1/20 0.40
CHRNA4 P43681 1/20 0.40
CHRNB3 Q05901 1/20 0.40
ACHE P22303 1/20 0.40
HCRTR1 O43613 1/20 0.40
HCRTR2 O43614 1/20 0.40
DPP4 P27487 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29007901 1.00 SSTR4 (0.44) SSTR4CHRNB4CHRNA3LTA4HCHRNB1
SCHEMBL14377503 0.85 CHRNB4 (0.44) CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4
SCHEMBL29007903 0.84 SSTR4 (0.46) SSTR4CHRNB4CHRNA3CHRNB1CHRNB2
SCHEMBL29007905 0.84 SSTR4 (0.46) SSTR4CHRNB4CHRNA3CHRNB1CHRNB2
SCHEMBL29007782 0.84 SSTR4 (0.47) SSTR4
SCHEMBL29007780 0.84 SSTR4 (0.47) SSTR4
SCHEMBL29007897 0.82 CHRNB4 (0.41) CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4
SCHEMBL29007896 0.82 CHRNB4 (0.41) CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4
SCHEMBL14377114 0.81 SMN1; SMN2 (0.50) CHRNB4CHRNA3LTA4HCHRNB1CHRNB2
SCHEMBL30181228 0.81 SSTR4 (0.44) SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116157392-A Compounds targeting RNA binding proteins or RNA modification proteins 雷多纳治疗公司 2023-05-23 CN disclosed