SCHEMBL290080

SCHEMBL290080

O=c1c(O)c(-c2ccccc2O)oc2ccccc12

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NMUR2 Q9GZQ4 4/20 0.71
KDM4E B2RXH2 7/20 0.68
MEN1 O00255 6/20 0.68
KMT2A Q03164 6/20 0.68
CYP3A4 P08684 6/20 0.68
MAPK1 P28482 4/20 0.68
ALOX15 P16050 4/20 0.68
TP53 P04637 3/20 0.68
LMNA P02545 2/20 0.68
CA12 O43570 1/20 0.68
CA1 P00915 1/20 0.68
CA2 P00918 1/20 0.68
ABCB1 P08183 1/20 0.68
CALM1 P0DP23 1/20 0.68
AR P10275 1/20 0.68
PKM P14618 1/20 0.68
CYP1B1 Q16678 1/20 0.68
CA9 Q16790 1/20 0.68
HSD17B10 Q99714 5/20 0.66
ALDH1A1 P00352 4/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31675811 1.00 NMUR2 (0.71) NMUR2KDM4EMEN1KMT2ACYP3A4
SCHEMBL471860 0.90 NMUR2 (0.68) NMUR2KDM4EMEN1KMT2ACYP3A4
SCHEMBL3062193 0.86 KDM4E (0.72) NMUR2KDM4EMEN1KMT2ACYP3A4
SCHEMBL6834225 0.85 MEN1 (0.68) NMUR2KDM4EMEN1KMT2ACYP3A4
SCHEMBL1423153 0.85 NMUR2 (0.54) NMUR2KDM4EMEN1KMT2ACYP3A4
SCHEMBL5425962 0.84 MEN1 (0.66) NMUR2KDM4EMEN1KMT2ACYP3A4
SCHEMBL773152 0.83 NMUR2 (0.68) NMUR2KDM4EMEN1KMT2ACYP3A4
SCHEMBL157971 0.83 KDM4E (0.64) NMUR2KDM4EMEN1KMT2ACYP3A4
SCHEMBL15676117 0.83 NMUR2 (0.68) NMUR2KDM4EMEN1KMT2ACYP3A4
SCHEMBL16586869 0.83 NMUR2 (0.68) NMUR2KDM4EMEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1036 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025038960-A1 OLIGONUCLEOTIDES CONTAINING A LIGAND AT AN INTERNAL POSITION ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 WO claimed
CN-118085410-A Boron-based natural flavone brucite composite powder and preparation method and application thereof 江西广源新材料有限公司 2024-05-28 CN claimed
CN-117562060-A Temperature intelligent sensing algae-inhibiting flavone slow-release microsphere and preparation method thereof 浙江大学 2024-02-20 CN claimed
CN-117562061-A PH value intelligent sensing algae-inhibiting flavone slow-release microsphere and preparation method thereof 浙江大学 2024-02-20 CN claimed
CN-115364006-B Anti-aging barrier repairing composition and anti-aging barrier repairing skin care product 皓雨(广州)化妆品制造有限公司 2024-02-09 CN claimed
WO-2024026037-A1 ER-BETA ESTROGENIC COMPOUNDS AND METHODS OF USE IATERION, INC. (US) 2024-02-01 WO claimed
WO-2023150072-A1 COMPOSITIONS AND METHODS FOR THE PRESERVATION OF PLANT MATTER SINCLAIR DAVID A (US) 2023-08-10 WO claimed
CN-114958730-A Muscle stem cell proliferation medium, differentiation medium and application thereof 南京农业大学 2022-08-30 CN claimed
US-20220249431-A1 ANTIMYCOTIC Karl-Franzens-Universität Graz (AT) 2022-08-11 US claimed
EP-4003522-A1 ANTIMYCOTIC Karl-Franzens-Universität Graz (AT) 2022-06-01 EP claimed
WO-2003035897-A2 ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY BURTON MICHAEL (GB) 2003-05-01 WO claimed
JP-2003504327-A 2003-02-04 JP claimed
EP-1223928-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS Prendergast, Patrick Thomas (IE) 2002-07-24 EP claimed
US-6329422-B1 ENHANCING, STIMULATING CHLORIDE TRANSPORT IN EPITHELIAL CELLS; FLAVONE OR ISOFLAVONE OR A STEREOISOMER THEREOF. CHILDREN'S HOSPITAL OAKLAND RESEARCH INSTITUTE 2001-12-11 US claimed
WO-2001080855-A1 TELOMERASE INHIBITORS AND METHODS OF THEIR USE GERON CORPORATION (US) 2001-11-01 WO claimed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 WO claimed
EP-1024803-A1 FLAVONOIDS FOR CYSTIC FIBROSIS THERAPY Children's Hospital Medical Center of Northern California (US) 2000-08-09 EP claimed
WO-1999018953-A1 FLAVONOIDS FOR CYSTIC FIBROSIS THERAPY CHILDREN'S HOSPITAL MEDICAL CENTER OF NORTHERN CALIFORNIA (US) 1999-04-22 WO claimed
EP-0245931-A2 Nodulation inducing factors LUBRIZOL GENETICS INC. (US) 1987-11-19 EP claimed
EP-0024731-B1 A PHOTOSTABLE ANTHOCYANIC COLORANT COMPOSITION AND ITS USE IN A FOOD COMPOSITION THE COCA-COLA COMPANY (US) 1983-09-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220249431-A1 ANTIMYCOTIC ETF1, FOXM1, RIF1 NMUR2 4053/4885KDM4E 1705/4885MEN1 1320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.