Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.38 |
| ▸ | FDPS | P14324 | 9/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29006845 | 1.00 | TSHR (0.42) | TSHRTHRBGGPS1FDPSEPHX1 | |
| SCHEMBL1970762 | 0.97 | TSHR (0.37) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL1971851 | 0.89 | TSHR (0.33) | TSHRTHRBFDPS | |
| SCHEMBL27947144 | 0.83 | TSHR (0.53) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL18708717 | 0.81 | TSHR (0.44) | TSHRTHRBGGPS1FDPSSMPD1 | |
| Octane SCHEMBL9281542 | 0.80 | TSHR (0.50) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL10893467 | 0.80 | TSHR (0.47) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL2255667 | 0.78 | TSHR (0.47) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL2255900 | 0.78 | TSHR (0.47) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL16594701 | 0.78 | TSHR (0.47) | TSHRTHRBGGPS1FDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117941116-A | Ionic binders for solid state electrodes | 迪金大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-117586265-A | Nitrogen-containing heterocyclic compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-116761609-A | Substituted pyrazolo [1,5-a ] pyrimidin-7-amine derivatives, compositions thereof and pharmaceutical uses thereof | 上海海雁医药科技有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-116669736-A | Fused heterocyclyl-substituted cyclohexanediimide derivatives, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-113861220-B | Tricyclic pyrimidinone compounds, methods of making, compositions and uses thereof | 上海纽思克生物科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-116171155-A | Pyrido [2,3-d ] pyrimidine-2 (1H) -ketone derivative, preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-116096720-A | Dihydropyrrolo [2,3-d ] pyridazin-7-one derivatives, preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-05-09 | — | — | CN | disclosed |