Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | INPPL1 | O15357 | 8/20 | 0.36 |
| ▸ | INPP5A | Q14642 | 5/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | INPP5B | P32019 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23488 | 0.98 | HTR2A (0.40) | HTR2AHTR1AHTR2CHTR2BINPPL1 | |
| SCHEMBL29356973 | 0.98 | HTR2A (0.40) | HTR2AHTR1AHTR2CHTR2BINPPL1 | |
| Ammonia Solution, Strong SCHEMBL20492883 | 0.97 | HTR2A (0.40) | HTR2AHTR1AHTR2CHTR2BINPPL1 | |
| SCHEMBL17668115 | 0.97 | HTR2A (0.40) | HTR2AHTR1AHTR2CHTR2BINPPL1 | |
| SCHEMBL31324009 | 0.97 | HTR2A (0.40) | HTR2AHTR1AHTR2CHTR2BINPPL1 | |
| SCHEMBL5058499 | 0.97 | HTR2A (0.40) | HTR2AHTR1AHTR2CHTR2BINPPL1 | |
| Phosphoric Acid SCHEMBL8156858 | 0.97 | HTR2A (0.40) | HTR2AHTR1AHTR2CHTR2BINPPL1 | |
| Inositol SCHEMBL2831131 | 0.93 | HTR2A (0.38) | HTR2AHTR1AHTR2CHTR2BINPPL1 | |
| SCHEMBL17668116 | 0.92 | HTR2A (0.37) | HTR2AHTR1AHTR2CHTR2BINPPL1 | |
| Phosphoric Acid SCHEMBL8156857 | 0.88 | HTR2A (0.32) | HTR2AHTR1AHTR2CHTR2BNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114133551-B | Pyrimidine polyether and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-114133551-A | Pyrimidyl polyether and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-114133551-B | Pyrimidine polyether and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-114133551-A | Pyrimidyl polyether and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-03-04 | — | — | CN | disclosed |