Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14294672 | 0.79 | CHRM2 (0.45) | ALDH1A1CHRM2CHRM3KMT2AL3MBTL1 | |
| SCHEMBL28883975 | 0.76 | KMT2A (0.41) | ALDH1A1KMT2AL3MBTL1HPGDKDM4E | |
| SCHEMBL29009118 | 0.74 | CYP19A1 (0.53) | ALDH1A1KMT2AL3MBTL1HPGDKDM4E | |
| SCHEMBL29009125 | 0.74 | TSHR (0.49) | KMT2AHSD17B10NPC1RAB9AMEN1 | |
| SCHEMBL29009115 | 0.72 | TLR8 (0.51) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL11813984 | 0.71 | HSD17B10 (0.44) | L3MBTL1HPGDKDM4EHSD17B10HTT | |
| SCHEMBL7713800 | 0.71 | KMT2A (0.48) | ALDH1A1KMT2AL3MBTL1HPGDKDM4E | |
| SCHEMBL30434618 | 0.71 | KMT2A (0.38) | ALDH1A1KMT2AL3MBTL1HPGDKDM4E | |
| SCHEMBL29009114 | 0.71 | TLR8 (0.50) | KMT2AMEN1SMN1; SMN2MAPTTSHR | |
| SCHEMBL7918782 | 0.71 | KMT2A (0.52) | ALDH1A1CHRM2CHRM3KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178286-B | N (N)2Alkyl substituted triazole derivative and synthetic method and application thereof | 华东师范大学 | 2024-12-03 | — | — | CN | disclosed |
| CN-116178286-A | High-selectivity N 2 Alkyl substituted triazole derivative and synthetic method and application thereof | 华东师范大学 | 2023-05-30 | — | — | CN | disclosed |