SCHEMBL29009142

SCHEMBL29009142

O=C(/C=C/c1ccccc1)Oc1ccc(O)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.73
AKR1B10 O60218 4/20 0.59
AKR1B1 P15121 4/20 0.59
CA12 O43570 4/20 0.59
CA7 P43166 4/20 0.59
CA9 Q16790 4/20 0.59
CA14 Q9ULX7 4/20 0.59
CA4 P22748 2/20 0.59
CA6 P23280 2/20 0.59
CA5A P35218 2/20 0.59
CA5B Q9Y2D0 2/20 0.59
MAPT P10636 3/20 0.59
MAOB P27338 2/20 0.59
CYP3A4 P08684 2/20 0.59
HSPD1 P10809 2/20 0.59
HSPE1 P61604 2/20 0.59
MEN1 O00255 2/20 0.59
F3 P13726 2/20 0.59
ALDH2 P05091 1/20 0.59
CYP19A1 P11511 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30825756 1.00 KMT2A (0.73) KMT2AAKR1B10AKR1B1CA12CA7
SCHEMBL14634510 0.93 KMT2A (0.68) KMT2AAKR1B10AKR1B1CA12CA7
SCHEMBL14634511 0.93 KMT2A (0.68) KMT2AAKR1B10AKR1B1CA12CA7
SCHEMBL16982630 0.93 KMT2A (0.83) KMT2AAKR1B10AKR1B1MAPTMAOB
SCHEMBL29009143 0.91 CA12 (0.67) KMT2AAKR1B10AKR1B1CA12CA7
SCHEMBL28985864 0.90 KMT2A (0.65) KMT2AAKR1B10AKR1B1CA12CA7
SCHEMBL28985862 0.90 KMT2A (0.65) KMT2AAKR1B10AKR1B1CA12CA7
Phenyl Cinnamate SCHEMBL1055161 0.89 KMT2A (0.77) KMT2AAKR1B10AKR1B1MAPTMAOB
Phenyl Cinnamate SCHEMBL1055160 0.89 KMT2A (0.77) KMT2AAKR1B10AKR1B1MAPTMAOB
SCHEMBL679710 0.88 CA12 (0.72) KMT2AAKR1B10AKR1B1CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974687-A Preparation method of hydroquinone ester derivative with tyrosinase inhibitory activity 西南林业大学 2023-04-18 CN disclosed