Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.45 |
| ▸ | FLT3 | P36888 | 5/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30382124 | 1.00 | ATR (0.46) | ATRFGFR1KDRPDGFRBFGFR2 | |
| SCHEMBL29009528 | 0.87 | ATR (0.47) | ATRFGFR1KDRPDGFRBFGFR2 | |
| SCHEMBL30382066 | 0.87 | ATR (0.47) | ATRFGFR1KDRPDGFRBFGFR2 | |
| SCHEMBL29009524 | 0.86 | FGFR1 (0.56) | FGFR1KDRPDGFRBFGFR2FGFR3 | |
| SCHEMBL30382361 | 0.86 | FGFR1 (0.56) | FGFR1KDRPDGFRBFGFR2FGFR3 | |
| SCHEMBL31006257 | 0.83 | FGFR1 (0.56) | ATRFGFR1KDRPDGFRBFGFR2 | |
| SCHEMBL30382459 | 0.81 | FGFR1 (0.46) | ATRFGFR1KDRPDGFRBFGFR2 | |
| SCHEMBL29009492 | 0.81 | FGFR1 (0.46) | ATRFGFR1KDRPDGFRBFGFR2 | |
| SCHEMBL30382584 | 0.81 | CHEK1 (0.45) | FGFR1KDRFLT3FLT1PDPK1 | |
| SCHEMBL29009490 | 0.81 | CHEK1 (0.45) | FGFR1KDRFLT3FLT1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217551-A | Substituted indazole or azaindazole compounds and application thereof | 河南中医药大学 | 2023-06-06 | — | — | CN | claimed |
| CN-116217551-A | Substituted indazole or azaindazole compounds and application thereof | 河南中医药大学 | 2023-06-06 | — | — | CN | disclosed |